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Precise Protein Photolithography (P3): High Performance Biopatterning Using Silk Fibroin Light Ch...
A wafer-scale high resolution patterning of bio-microstructures is achieved using precise protein photolithography. The application of these micropatterned structures as cellular substrate for the successful spatial guidance of fetal neural stems cells using well-defined silk fibroin light chain ...[ Learn more ]
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Inkjet Printing of Regenerated Silk Fibroin: From Printable Forms to Printable Functions
Cells “spin” a mineralized spiderweb: BMP-2-loaded silk material is inkjet-printed into a spiderweb pattern on a Petri dish and seeded with mesenchymal stem cells (MSCs). Upon culture in osteogenic media, the osteo-inductive print topographically controls the differentiation of MSCs, resulting ...[ Learn more ]
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All-water-based electron-beam lithography using silk as a resist
The use of silk as a natural and biofunctional resist for electron-beam lithography is presented. The process is entirely water-based, starting with the silk aqueous solution and ending with simple development of the exposed silk film in water. Because of its polymorphic crystalline structure, si...[ Learn more ]
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Protein-Protein Nanoimprinting of Silk Fibroin Films
Protein-protein imprinting of silk fibroin is introduced as a rapid, high-throughput method for the fabrication of nanoscale structures in silk films, through the application of heat and pressure. Imprinting on conformal surfaces is demonstrated with minor adjustments to the system, at resolution...[ Learn more ]