RESUME
Professor Hongju Mao received her M.S degree in Genetics from Shanghai Medical College of Fudan University and her PhD in Biosensors from Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences and as a Royal Society Visiting Research Fellow in the School of Biomedical Sciences, University of Leeds, UK from 2005 to 2006.
In 2005, as a technical director of project, Professor Mao together with his colleagues, had successfully accomplished the clinical evaluation of oligonucleotide chips for genotyping hepatitis C virus and got first class national new drug certificate.
At present, she work on the research in early detection of major disease based on microfluidic chip and biosensor technology. She published more than 80 papers, and applied more than 35 patents. She guest professor of Fuzhou University.
WORK EXPERIENCE
07, 2006–Present: Research Professor, DNAChip group, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, P. R. China
02, 2005 –03, 2006: Royal Society Visiting Research Fellow in the School of Biomedical Sciences, University of Leeds, UK
07,2000 –02,2005: Research Associate Professor, DNAChip group ,Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, P. R. China
EDUCATION
Ph.D., Biosensors, 2008, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences
M.S., Genetics, 2000, Shanghai Medical College of Fudan University
B.S., Biology, 1992, He Nan Normal University
SELECTED PUBLICATIONS
1)Anran Gao, Xun Yang, Jing Tong, Lin Zhou, Yuelin Wang, Jianlong Zhao, Hongju Mao*, Tie Li*. Multiplexed detection of lung cancer biomarkers in patients serum with CMOS-compatible silicon nanowire arrays. Biosens Bioelectron., 2017,91:484-488.
2)Lin Zhou, Hongju Mao*, Chunyan Wu, Lin Tang, Zhenhua Wu, Hao Sun, Honglian Zhang, Hongbo Zhou, Chunping Jia, Qinghui Jin, Xianfeng Chen, Jianlong Zhao*. Label-free graphene biosensor targeting cancer molecules based on non-covalent modification. Biosens Bioelectron., 2017,87:701-707.
3)Zule Cheng, Yanan Bai, Ping Wang, Zhenhua Wu, Lin Zhou, Ming Zhong, Qinghui Jin, Jianlong Zhao*, Hailei Mao*, Hongju Mao*. Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis. Oncotarget, 2017,8(8): 13329-13337
4)Yunfei Ma, Yanan Bai, Hailei Mao, Qunying Hong, Dawei Yang, Honglian Zhang, Fangming Liu, Zhenhua Wu, Qinghui Jin, Hongbo Zhou, Jian Cao, Jianlong Zhao, Xinhua Zhong*, Hongju Mao*. A panel of promoter methylation markers for invasive and noninvasive early detection of NSCLC using a quantum dots-based FRET approach. Biosens Bioelectron., 2016, 85: 641-648.
5)Fangming Liu, Honglian Zhang, Zhenhua Wu, Haidao Dong, Lin Zhou, Dawei Yang, Yuqing Ge, Chunping Jia, Huiying Liu, Qinghui Jin, Jianlong Zhao, Qiqing Zhang , Hongju Mao*. Highly sensitive and selective lateral flow immunoassay based on magnetic nanoparticles for quantitative detection of carcinoembryonic antigen. Talanta, 2016, 161: 205-210.
6)Zhenhua Wu, Tianle Ma, Jean-Luc Coll, Fangming Liu, Honglian Zhang, Yunfei Ma, Zhishuo Wang, Qinghui Jin, Hongju Mao*, Jianlong Zhao*. Detection of KRAS mutations using double-stranded toehold-exchange probes. Biosens Bioelectron., 2016, 15;80:175-81
7)Lin Zhou, Kun Wang, Zhenhua Wu, Haidao Dong, Hao Sun, Xuanhong Cheng, Honglian Zhang, Hongbo Zhou, Chunping Jia, Qinghui Jin, Hongju Mao*, Jean-Luc Coll*, Jianlong Zhao*. Investigation of Controllable Nanoscale Heat-Denatured Bovine Serum Albumin Films on Graphene. Langmuir, 2016, 32(48): 12623-12631.
8)Yunfei Ma, Honglian Zhang, Fangming Liu, Zhenhua Wu, Shaohua Lu, Qinghui Jin, Jianlong Zhao, Xinhua Zhong, Hongju Mao*. Highly sensitive detection of DNA methylation levels by using a quantum dot-based FRET method. Nanoscale, 2015, 7, 17547–17555 (SCI, IF 7.39)
9)Ping Wang, Fengxiang Jing, Gang Li, Zhenhua Wu, Zule Cheng, Jishen Zhang, Honglian Zhang, Chunping Jia, Qinghui Jin, Hongju Mao*, Jianlong Zhao. Absolute quantification of lung cancer related microRNA by droplet digital PCR. Biosens Bioelectron. 2015,74, 836-842 (SCI, IF 6.45)
10)Ping Wang, Shaohua Lu, Hailei Mao, Yanan Bai, Tianle Ma, Zule Cheng, Honglian Zhang, Qinghui Jin, Jianlong Zhao, Hongju Mao*. Identification of biomarkers for the detection of early stage lung adenocarcinoma by microarray profiling of long noncoding RNAs. Lung Cancer, 2015, 88(2): 147-153. (SCI, IF 3.77)
11)Ping Wang, Dawei Yang, Honglian Zhang, Xuyu Wei, Tianle Ma, Zule Cheng, Qunying Hong, Jie Hu, Hanjing Zhuo, Yuanlin Song, Chunping Jia, Fengxiang Jing, Qinghui Jin, Chunxue Bai, Hongju Mao*, Jianlong Zhao. Early detection of lung cancer in serum by a panel of microRNA biomarkers. Clin. Lung Cancer, 2015, 16(4):313-9. (SCI, IF 3.2)
12)Na Lu, Anran Gao, Pengfei Dai, Hongju Mao, Xiaolei Zuo, Chunhai Fan, Yuelin Wang*, Tie Li*. Ultrasensitive Detection of Dual Cancer Biomarkers with Integrated CMOS-Compatible Nanowire Arrays. Anal Chem., 2015, 87(22):11203-11208
13)Bin Jin, Ping Wang, Hongju Mao*, Bing Hu, Honglian Zhang, Zule Cheng, Zhenhua Wu, Xiaojun Bian, Chunping Jia, Fengxiang Jing, Qinghui Jin, Jianlong Zhao. Multi-nanomaterial electrochemical biosensor based on label-free graphene for detecting cancer biomarkers. Biosens Bioelectron., 2014,55, 464-469
14)Anran Gao, Nengli Zou, Pengfei Dai, Na Lu, Tie Li*, Yuelin Wang*, Jianlong Zhao, Hongju Mao*. Signal-to-noise ratio enhancement of silicon nanowires biosensor with rolling circle amplification. Nano letters, 2013, 13(9): 4123-4130.
15)Jimin Zhu, Nengli Zou, Hongju Mao*, Ping Wang, Danian Zhu, Huoyan Ji, Hui Cong, Changjiang Sun, Huimin Wang, Feng Zhang, Juying Qian, Qinghui Jin*, Jianlong Zhao*. Evaluation of a modified lateral flow immunoassay for detection of high-sensitivity cardiac troponin I and myoglobin. Biosens Bioelectron., 2013, 42: 522-525.
16)Yasi Xing, Ping Wang, Yucui Zang, Yuqing Ge, Qinghui Jin, Jianlong Zhao, Xia Xu,* Guoqiang Zhao*, Hongju Mao*. A colorimetric method for H1N1 DNA detection using rolling circle amplification. Analyst, 2013, 138(12): 3457-3462.
17)Honglian Zhang, Gang Li, Lingying Liao, HongJu Mao, Qinghui Jin, Jianlong Zhao. Direct detection of cancer biomarkers in blood using a “place n play” modular pump. Biomicrofluidics , 2013,7: 034105-1-10
18)Xinxin Fang, Huanqian Zhang, Feng Zhang, Fengxiang Jing, Hongju Mao, Qinghui Jin*, Jianlong Zhao*. Real-time monitoring of strand-displacement DNA amplification by a contactless electrochemical microsystem using interdigitated electrodes. Lab Chip, 2012, 12, 3190–3196.
19)Jimin Zhu, Nengli Zou, Danian Zhu, Jin Wang, Qinghui Jin, Jianlong Zhao, Hongju Mao*. Simultaneous Detection of High-Sensitivity Cardiac Troponin I and Myoglobin by Modified Sandwich Lateral Flow Immunoassay. Clin Chem. 2011,57(12):1732-1738
20)Xiang Wang, Xinhui Lou, Yi Wang, Qingchuan Guo, Zheng Fang, Xinhua Zhong, Hongju Mao*, Qinghui Jin, Lei Wu, Hui Zhao, Jianlong Zhao*. QDs-DNA nanosensor for the detection of hepatitis B virus DNA and the single-base mutants. Biosens Bioelectron., 2010, 25(8): 1934-1940.
