He was born in December 25, 1917 in Pujiang of Zhejiang province. In 1939, he graduated from the Department of Aeronautical Engineering of Tianjin Beiyang University. He once served as a designer and engineer of the Leiyun central aircraft factory of Yunnan as well as the central machine factory of Kunming. In 1943, he went abroad to study metallurgy in the Pittsburgh Carnegie Institute of Technology, and got his doctor degree there.
After his graduation, he continued to study at the Institute of Metal Research of the same university as a postdoctoral student. In 1949, he began to work as the chief research engineer of the Department of materials at the University of stannus. At the end of 1950, he returned to China and was appointed by Northern Chiao Tung University as a professor of Metallurgy Department in 1951. Later hewas transferred to the Experimental Laboratory of Chinese Academy of Sciences (now it has turned into Shanghai Institute of microsystems and information technologylinked to Chinese Academy ofSciences) in September of the same year. In 1961, he acted simultaneously as the associate director of the Shanghai metallurgical Ceramic Institute as well as a director of the academic committee of it.
In 1980, he was elected as the academician of the Chinese Academy of Sciences and departed from the world in May 24, 2008.Ziliang Wu led and completed the task of developing the special resistance wire urgently needed by the war to resist U.S. aggression and aid Korea , ordered by Central Military Commission of China in 1954. In 1950s, success has been achieved in replacing the scarce chromium with rich elements,such as manganese and aluminum, to develop the substitute steel of 40X low alloy steel which was made by Soviet Union, and played a pioneering role in the establishment of China's alloy steel system. In 1960s, he worked hand in hand with relevant scientific research personnel, and successfully developed the "vacuum valve", a key component for enriching uranium 235,which made an important contribution to the first atomic bomb explosion in China. In 1956, he won the third prize of National Natural Science (rank first).
In 1984,he won the first prize of the National Invention Prize (rank first). In 1985, he obtained the national science and technology progress award.
In September,1999 ,he was awarded the "two bombs and one satellite meritorious medal" by the CPC Central Committee and the State Council and the Central MilitaryCommission jointly.He was born in Jiangshan County of Zhejiang province in May 22, 1926.
He graduated from the department of chemical engineering of Zhejiang University in July, 1950 and entered into Institute of Engineering Experiment Laboratory of the Chinese Academy of Sciences(now it has turned into Shanghai Institute of microsystems and information technology linked to Chinese Academy of Sciences). He once served as a researcher, director,and even as professor of Shanghai University ofscience and Technology and as a board member of China Institute of electronic . In 1995, he was elected as the academician of the Chinese Academy of engineering and died in March 27, 2013.